Linkage Projects - Grant ID: LP0211396

Funding Activity

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Funded Activity Summary

Characterisation and Stability of ISCOM Vaccines. ISCOMS® are particles comprising saponin, cholesterol and phospholipids which when mixed with proteins form potent vaccines. When proteins are associated with ISCOMs® a variety of different sized particles with various surface chemistries can be formed. This project aims to understand the physico-chemical mechanisms governing ISCOM® formation. This understanding will allow development of methods for controlling the size, characteristics and long-term stability of these particles. In addition the size and surface chemistry of the particles will be correlated with their effectiveness as vaccines. Both these outcomes will support the ongoing commercial development of ISCOM®-based vaccines at CSL.

Funded Activity Details

Start Date: 01-01-2002

End Date: 31-12-2005

Funding Scheme: Linkage Projects

Funding Amount: $205,366.00

Funder: Australian Research Council