Linkage Projects - Grant ID: LP0210513

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/LP0210513

Funding Status
Closed

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Funded Activity Summary

Development of SELEX technology (Systematic Evolution of Ligands by EXponential enrichment). A recently developed in vitro genetic selection technique has allowed the isolation of oligonucleotides that can bind target molecules with high affinity and specificity. The strategy know as SELEX (Systematic Evolution of Ligands by EXponential enrichment) uses protein biochemistry and PCR technology, with subsequent repeated rounds of selection and amplification, to screen vast libraries of oligonucleotides (RNA or DNA) for their ability to bind target proteins. This procedure will be developed by UNSW in collaboration with the biotech company BTF Plc., Ltd., to be used in two applications. The first is the research interest of UNSW and involves the development of aptamers against hepatitis C virus. The second lies within the interests of BTF and will involve the development of aptamers against the water borne pathogen Cryptosporidium parvum.

Funded Activity Details

Start Date: 12-07-2002

End Date: 11-07-2005

Funding Scheme: Linkage Projects

Funding Amount: $146,203.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Diagnostic Applications | Microbiology | Virology | Infectious Agents

ANZSRC Socio-Economic Objective (SEO)

Infectious diseases |

Other Keywords

Diagnostic Applications | Infectious Agents | Infectious diseases | Microbiology | Virology

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