Linkage Infrastructure, Equipment and Facilities - Grant ID: LE180100179

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/LE180100179

Funding Status
Closed

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Funded Activity Summary

Automated high resolution and high contrast cryo -TEM for three-dimensional structural biology. This project aims to establish a facility in automated, single-particle cryo-TEM and cryo-TEM tomography (Titan Krios) that will enable atomic and molecular structure research and three-dimensional subcellular and cellular imaging. The project will span all multiscale cryo-TEM modalities from the visualisation of cells, membranes and macromolecular complexes, through to near-atomic-resolution protein structure determination. Cryo-single particle analysis and tomography are recognised as revolutionary technologies in molecular structural biology and powerful enablers of future ground-breaking discovery. The project will deliver significant competitive advantage for Australia in leading-edge structure-based research, drug discovery, new opportunities for applied research and development, and showcasing science to the public.

Funded Activity Details

Start Date: 29-03-2018

End Date: 31-12-2019

Funding Scheme: Linkage Infrastructure, Equipment and Facilities

Funding Amount: $3,189,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Interactions (incl. Adhesion, Matrix, Cell Wall) | Biochemistry and Cell Biology | Structural Biology (incl. Macromolecular Modelling) | Macromolecular and Materials Chemistry not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Chemical Sciences | Scientific Instruments | Expanding Knowledge in the Biological Sciences |

Other Keywords

Biochemistry and Cell Biology | Cellular Interactions (incl. Adhesion, Matrix, Cell Wall) | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Chemical Sciences | Macromolecular and Materials Chemistry not elsewhere classified | Scientific Instruments | Structural Biology (incl. Macromolecular Modelling)

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