Linkage - CSIRO - Grant ID: LC0348594

Funding Activity

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Funded Activity Summary

Development of Novel Pesticidal Agents. We have discovered a family of naturally occurring plant proteins called the cyclotides that have potent insecticidal activity against Helicoverpa species, one of the major pests on cotton and corn in Australia and world wide. Preliminary evidence has shown that they also have activity against major pests to livestock in Australia, including sheep blowflies. To develop these proteins as potential pesticidal agents it is necessary to understand the structural basis for their activity. We will do this by chemically synthesising peptides with selected residues mutated to determine their effects on activity.

Funded Activity Details

Start Date: 28-11-2003

End Date: 27-11-2006

Funding Scheme: Linkage - CSIRO

Funding Amount: $193,035.00

Funder: Australian Research Council