Mid-Career Industry Fellowships - Grant ID: IM230100534

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/IM230100534

Funding Status
Active

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Funded Activity Summary

NOVEL MASS-SCALE BIOSYNTHESIS: TAILORING CHEMICAL LOGIC & BIOSYNTHESIS. No new antibiotics against Gram-negative ‘superbugs’ are expected to be available in the near future. We have exhausted the chemical space from the natural product pool and lack a fundamental understanding of antibiotics in nature, this is a major hurdle for antibiotic design targeting bacterial resistance. This proposal aims to engineer unique chemo-enzymatic platforms for the synthesis of new lipopeptide scaffolds which will significantly expand the chemical space available for novel antibiotic discovery. The development of these unique platforms will greatly expand our inventory of natural product antibiotics and will represent a major technological break-through for Australia's biotechnology and pharmaceutical manufacturing sectors.

Funded Activity Details

Start Date: 01-07-2023

End Date: 30-06-2027

Funding Scheme: Mid-Career Industry Fellowships

Funding Amount: $874,096.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medicinal and biomolecular chemistry not elsewhere classified | Biomedical engineering not elsewhere classified | Medicinal and biomolecular chemistry |

ANZSRC Socio-Economic Objective (SEO)

Other Keywords

Antimicrobials, Antifungals and Biocides | Biomedical engineering not elsewhere classified | Human Pharmaceutical Products Not Elsewhere Classified | Medicinal and biomolecular chemistry | Medicinal and biomolecular chemistry not elsewhere classified

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