ARC Future Fellowships - Grant ID: FT230100138

Funding Activity

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Funded Activity Summary

Benchmarking the neurophysiology of human cortex models in vitro. This project aims to improve human brain models in vitro by developing an analytical tool benchmarking biophysical similarities to the adult human cortex. This project expects to generate new knowledge by testing for the first time the theory that integrating sensory-like inputs and awake/sleep-like cycles of electrical activity in vitro may complete the maturation of human brain organoid models. It will also generate new methods to simplify the analysis of multimodal path-clamping data (Patch-seq). Expected outcomes will facilitate research collaboration and the reproducibility of accurate experimental replicates of the human brain. This will provide significant benefits in the global race to understand human brain computation mechanisms.

Funded Activity Details

Start Date: 01-07-2023

End Date: 30-06-2027

Funding Scheme: ARC Future Fellowships

Funding Amount: $1,145,629.00

Funder: Australian Research Council