ARC Future Fellowships - Grant ID: FT230100084

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/FT230100084

Funding Status
Active

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Funded Activity Summary

Developing a new class of RNA delivery vehicle using synthetic virology. This project aims to develop robust protein cages derived from the empty shells of viruses, or capsids, to protect and deliver sensitive cargo such as RNA in agricultural settings. It will do so by directed evolution of non-infectious capsids in the lab. This will uncover the molecular mechanisms underpinning the response of viruses to chemical and biological signals and create a new class of RNA delivery vehicle. This synthetic biology approach combines virology and protein engineering to establish a platform biotechnology for stable and effective delivery. The project expects to demonstrate the potential of nature’s nanoparticles, virus capsids, to enhance the efficacy of RNA technologies in a wide range of applications.

Funded Activity Details

Start Date: 01-07-2023

End Date: 30-06-2027

Funding Scheme: ARC Future Fellowships

Funding Amount: $968,816.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Colloid and surface chemistry | Biochemistry and cell biology | Synthetic biology |

ANZSRC Socio-Economic Objective (SEO)

Other Keywords

Biochemistry and cell biology | Colloid and surface chemistry | Expanding Knowledge In the Biological Sciences | Expanding Knowledge In the Chemical Sciences | Synthetic biology

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