ARC Future Fellowships - Grant ID: FT220100405

Funding Activity

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Funded Activity Summary

Developing serial crystallography for room temperature structure & dynamics. This project aims to uncover the molecular structural dynamics of a bacterial enzyme responsible for protein folding in bacteria. This project expects to generate new knowledge to guide the development of a new type of antibacterial to circumvent antibiotic resistance. Expected outcomes of this project include new experimental, computational and simulation tools for dynamic X-ray crystallography including new capabilities at the Australian Synchrotron for very small microcrystals of any biomolecule. This would provide a powerful new tool for the Australian structural biology community that should accelerate fundamental discoveries, including facilitating high-resolution structure determination of membrane proteins and drug development.

Funded Activity Details

Start Date: 27-07-2023

End Date: 26-07-2027

Funding Scheme: ARC Future Fellowships

Funding Amount: $890,748.00

Funder: Australian Research Council