ARC Future Fellowships - Grant ID: FT220100159

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/FT220100159

Funding Status
Active

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Funded Activity Summary

Sensing biomechanical forces in the heart. Mechanosensitive ion channels are key molecules that define how each heart cell interacts with their physical environment. Yet how they enable cells to decode biomechanical cues remains poorly understood. At the heart of this problem is a lack of tools to quantify the force required for activation. This project aims to develop novel technologies to record the activity of these essential channels in a critical cell type within the heart, and use this information in addition to micro-engineering approaches to fully understand the role of these channels in force sensing and generation, at both the single cell and micro-tissue levels. This knowledge and technology has broad utility that extends far beyond cardiac biology into multiple fields.

Funded Activity Details

Start Date: 01-01-2023

End Date: 31-12-2026

Funding Scheme: ARC Future Fellowships

Funding Amount: $832,068.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and cell biology | Signal transduction | Receptors and membrane biology | Mechanobiology

ANZSRC Socio-Economic Objective (SEO)

Other Keywords

Biochemistry and cell biology | Expanding Knowledge In the Biological Sciences | Mechanobiology | Receptors and membrane biology | Signal transduction

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