ARC Future Fellowships - Grant ID: FT210100271

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/FT210100271

Funding Status
Active

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Funded Activity Summary

Multi-functional probes for global analysis of proteome stress in cells. This project aims to create a suite of multi-functional chemical probes to identify damaged proteins that undergo unfolding or specific modifications in cells under stress. These probes will not only generate fluorescence responses to reflect on protein quality control capacity but allow associated proteins and their networks to be identified in complex cellular environments, which is difficult to achieve by current methods. The expected outcome is to deliver new methodology for a comprehensive understanding of the correlation between quality control machinery, stress responses and cell functions. This should provide significant benefits, including contributing to fundamental knowledge on the molecular causes of neurodegenerative diseases.

Funded Activity Details

Start Date: 11-03-2022

End Date: 10-03-2026

Funding Scheme: ARC Future Fellowships

Funding Amount: $935,657.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology | Analytical Biochemistry | Cell Metabolism

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Chemical Sciences | Expanding Knowledge in the Biological Sciences |

Other Keywords

Analytical Biochemistry | Biochemistry and Cell Biology | Cell Metabolism | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Chemical Sciences

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