ARC Future Fellowships - Grant ID: FT200100798

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/FT200100798

Funding Status
Active

Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the .

Funded Activity Summary

Cracking post-translational modification codes in high molecular definition. This project aims to markedly improve the analysis of post-translational modifications (PTM) via intact protein mass spectrometry. Differences in the PTM forms of a protein (modforms) can be crucial in many physiological and metabolic processes. However, current conventional methods cannot accurately separate nor fully assign most protein modforms. A recent discovery has resulted in the ability to separate whole protein ions that have the same mass, charge, and collision cross section, but subtly different charge sites. This project aims to leverage this breakthrough by developing novel approaches for separating intact protein modforms and mapping PTM sites. This is expected to be important for future biological discovery.

Funded Activity Details

Start Date: 04-01-2021

End Date: 03-01-2025

Funding Scheme: ARC Future Fellowships

Funding Amount: $911,904.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Analytical Chemistry | Analytical Spectrometry

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Chemical Sciences | Expanding Knowledge in the Biological Sciences |

Other Keywords

Analytical Chemistry | Analytical Spectrometry | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Chemical Sciences

Related Links