ARC Future Fellowships - Grant ID: FT200100401

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/FT200100401

Funding Status
Active

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Funded Activity Summary

Tracking DNA repair dynamics in the nuclear landscape of a living cell. This project aims to track DNA repair factor recruitment in the nuclear landscape of a living cell and quantify the role of nucleus architecture in maintenance of genome integrity. By coupling advanced fluorescence microscopy with a novel DNA double strand break inducible cell system, this project expects to uncover how the nucleus spatially coordinates DNA damage detection, assessment and repair in real time. This research is important because DNA damage threatens organism survival and this project has the potential to define how this genomic threat is resolved at the single molecule level. The benefit of this research is a fundamental insight into DNA repair biology and development of imaging technology to quantify genome function.

Funded Activity Details

Start Date: 01-04-2021

End Date: 31-03-2025

Funding Scheme: ARC Future Fellowships

Funding Amount: $876,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Protein Trafficking | Biochemistry and Cell Biology | Biological Physics |

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences | Expanding Knowledge in Technology

Other Keywords

Biochemistry and Cell Biology | Biological Physics | Expanding Knowledge in Technology | Expanding Knowledge in the Biological Sciences | Protein Trafficking

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