ARC Future Fellowships - Grant ID: FT190100645

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/FT190100645

Funding Status
Active

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Funded Activity Summary

The Systems Biochemistry of Adaptation in Cellular Protein Networks. A living cell must process and interpret a host of diverse signals using a complex network of interacting proteins inside the cell. The detailed molecular mechanisms by which cells exhibit adaptation to these signals remains a fundamental question in biology. This project aims to develop a novel mathematical framework for analysing the capacity of intracellular protein interactions to contribute to cellular adaptation, along with a novel methodology for validating mathematical models against experimental data. These innovations offer a completely fresh approach to identifying and modulating the adaptive capacities of living cells, which may contribute to overcoming the problem of drug resistance in future therapeutic development.

Funded Activity Details

Start Date: 24-02-2020

End Date: 23-02-2024

Funding Scheme: ARC Future Fellowships

Funding Amount: $730,432.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biological Mathematics | Applied Mathematics | Systems Biology

ANZSRC Socio-Economic Objective (SEO)

Cancer and Related Disorders | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Mathematical Sciences |

Other Keywords

Applied Mathematics | Biological Mathematics | Cancer and Related Disorders | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Mathematical Sciences | Systems Biology

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