ARC Future Fellowships - Grant ID: FT190100403

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/FT190100403

Funding Status
Active

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Funded Activity Summary

Genetic networks regulating gene silencing by intronic repeat expansions . Changes in the copy number of DNA repeats are associated with phenotypic variations in several species. Expansions of DNA repeats underlie several human genetic diseases, including Friedreich’s ataxia. The molecular mechanisms that mediate these genetic abnormalities are currently unclear. This project aims to identify the novel genetic pathways and mechanisms mediating these genetic disorders. Using a plant model in an innovative way this project will discover novel genes, uncover fundamental molecular mechanisms and reveal the genetic networks that govern gene silencing caused by triplet repeat expansions. This project, in addition to revealing fundamental biological mechanisms, will also have implications for human disease.

Funded Activity Details

Start Date: 01-02-2020

End Date: 31-01-2024

Funding Scheme: ARC Future Fellowships

Funding Amount: $766,770.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Epigenetics (incl. Genome Methylation and Epigenomics) | Gene Expression (incl. Microarray and other genome-wide approaches) | Plant Developmental and Reproductive Biology | Genetics

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences |

Other Keywords

Epigenetics (incl. Genome Methylation and Epigenomics) | Expanding Knowledge in the Biological Sciences | Gene Expression (incl. Microarray and other genome-wide approaches) | Genetics | Plant Developmental and Reproductive Biology

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