ARC Future Fellowships - Grant ID: FT190100265

Funding Activity

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Funded Activity Summary

DNA repair: a critical quality control mechanism in the female germ line. This project aims to investigate the fundamental biological mechanisms required for the production of high quality gametes, which underpin female fertility and the propagation of all sexually reproducing species. By taking advantage of unique mouse and avian models, this project expects to define the role of the DNA repair protein TOP3A in the successful completion of meiosis and it's requirement for the survival and genetic integrity of gametes throughout their lifespan. In doing so, the intended outcome of this project is to dramatically improve our understanding of quality control in the female germ line. This should provide significant benefits to Australia by positioning it as a world leader in the field of Reproductive Science.

Funded Activity Details

Start Date: 01-01-2020

End Date: 31-12-2023

Funding Scheme: ARC Future Fellowships

Funding Amount: $853,284.00

Funder: Australian Research Council