ARC Future Fellowships - Grant ID: FT180100653

Funded Activity Summary

Epigenetic inheritance: how does it work? This project aims to determine the mechanisms responsible for the inheritance of acquired traits. Sometimes the environment can have effects on the phenotype of not only the exposed individual, but also their children and grandchildren. While it is clear that this can occur, what is not clear is the mechanism by which this happens and the frequency at which it happens. This project will use the model organism Caenorhabditis elegans, innovative new techniques for the discovery of low abundance RNA molecules, and fluorescence microscopy to analyse structures within the cell nucleus to determine what the molecular mechanism is by which this "transgenerational epigenetic inheritance" occurs. This will have an impact on evolutionary theory, as well as long-term consequences for the understanding of human health and disease, and the impact of a changing climate on agriculture.

Funded Activity Details

Start Date: 14-01-2019

End Date: 31-12-2023

Funding Scheme: ARC Future Fellowships

Funding Amount: $768,125.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Epigenetics (incl. Genome Methylation and Epigenomics) | Genome Structure and Regulation | Genetics

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Medical and Health Sciences |

Other Keywords

Epigenetics (incl. Genome Methylation and Epigenomics) | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Medical and Health Sciences | Genetics | Genome Structure and Regulation

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