ARC Future Fellowships - Grant ID: FT180100397

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/FT180100397

Funding Status
Active

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Funded Activity Summary

The structural biology of trace metal trafficking across membranes. This project aims to investigate how essential trace element nutrients are recognised and specifically acquired and expelled by bacterial cells. Cells are surrounded by biomembranes that separate and protect them from their environments. Embedded within these membranes are proteins that perform essential functions. In bacteria, membrane proteins are responsible for the uptake and elimination of trace elements that are required for survival. This project will investigate the features of integral membrane proteins that allow discrimination between cargo, by defining their three dimensional architectures using X-ray crystallography. This will contribute to the field of membrane protein structural biology and fundamental discoveries in the area of cellular trace element homeostasis and toxicity.

Funded Activity Details

Start Date: 01-03-2019

End Date: 31-12-2023

Funding Scheme: ARC Future Fellowships

Funding Amount: $878,125.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology | Structural Biology (incl. Macromolecular Modelling)

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences |

Other Keywords

Biochemistry and Cell Biology | Expanding Knowledge in the Biological Sciences | Structural Biology (incl. Macromolecular Modelling)

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