ARC Future Fellowships - Grant ID: FT180100027

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/FT180100027

Funding Status
Active

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Funded Activity Summary

The role of immuno-exosomes in innate immunity. This project aims to determine the role of exosomes (EV) in innate immunity. Exosomes are extracellular vesicles secreted by mammalian cells that have an important biological function in intercellular communication by transferring biologically active proteins, lipids, and RNAs to neighbouring or distant cells. Following exposure to a foreign organism, cells dynamically change the protein composition of the EV they secrete. While this data supports a role for EV as key players in innate immunity, a full understanding of the biological relevance of these vesicles and how they serve as a cellular defence mechanism is lacking. This project will provide significant benefits such as addressing key questions in EV biology and providing new fundamental insights into a novel and poorly understood component of the innate immune response.

Funded Activity Details

Start Date: 01-01-2019

End Date: 31-12-2022

Funding Scheme: ARC Future Fellowships

Funding Amount: $854,125.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Virology | Immunology | Innate Immunity

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences |

Other Keywords

Expanding Knowledge in the Biological Sciences | Immunology | Innate Immunity | Virology

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