ARC Future Fellowships - Grant ID: FT170100392

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/FT170100392

Funding Status
Closed

Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the .

Funded Activity Summary

Exploring metabotropic glutamate receptor 5 bias, allostery and heteromers. This project aims to provide novel mechanistic and structural insights into metabotropic glutamate receptor 5 (mGlu5) function. The mGlu5 is an essential regulator of neurotransmission and higher order brain functions including learning and memory. This project expects to expand knowledge of the fundamental biological processes engaged by mGlu5 through exploration of three novel paradigms of receptor activity: allostery, bias and heteromerisation. Expected outcomes also include generation of new pharmacological tools through interdisciplinary collaborative research between multiple institutions. There is significant expected economic benefit through commercialisation of new tools and facilitation of novel drug discovery.

Funded Activity Details

Start Date: 01-07-2017

End Date: 30-12-2021

Funding Scheme: ARC Future Fellowships

Funding Amount: $788,487.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Pharmacology and Pharmaceutical Sciences | Basic Pharmacology | Structural Biology (incl. Macromolecular Modelling) | Biologically Active Molecules

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences |

Other Keywords

Basic Pharmacology | Biologically Active Molecules | Expanding Knowledge in the Biological Sciences | Pharmacology and Pharmaceutical Sciences | Structural Biology (incl. Macromolecular Modelling)

Related Links