ARC Future Fellowships - Grant ID: FT160100143

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/FT160100143

Funding Status
Closed

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Funded Activity Summary

Evolution and functional impact of gene silencing by hairpin derived RNAs. This project aims to study RNA-mediated gene silencing in genome evolution. RNA interference (RNAi) has been widely used as an experimental tool since its Nobel Prize-winning discovery in 1998, but little is known about endogenous RNAi or its evolution. This project uses bioinformatics, high-throughput sequencing and molecular approaches to study hpRNAs, a class of small interfering RNAs, their adaptive evolution across fly species and vertebrates, and their functional effect on testis morphogenesis and distortion of female/male sex-ratio. The project also studies splicing-dependent small RNAs and miRNA-target interaction. This research could have applications from animal development to human pathology.

Funded Activity Details

Start Date: 15-08-2017

End Date: 31-12-2021

Funding Scheme: ARC Future Fellowships

Funding Amount: $680,632.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Applied Statistics | Genome Structure and Regulation | Bioinformatics | Genetics

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Information and Computing Sciences | Expanding Knowledge in the Biological Sciences | Application Software Packages (excl. Computer Games) |

Other Keywords

Application Software Packages (excl. Computer Games) | Applied Statistics | Bioinformatics | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Information and Computing Sciences | Genetics | Genome Structure and Regulation

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