ARC Future Fellowships - Grant ID: FT160100083

Funding Activity

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Funded Activity Summary

How the immune system recognises vitamin B-based allergies. This project aims to evaluate the range of molecules that can stimulate vitamin B-reactive T cells in mammals and amphibians, and the degree of conservation or variation in these molecules among diverse microorganisms. T cells are immune cells that recognise foreign molecules, including peptides, lipids and vitamin B metabolites, bound to specialised antigen-presenting molecules. In mammals, Mucosal Associated Invariant T cells, still poorly understood, recognise Vitamin B-based molecules. Combining immunology with structural biology and chemistry, this project aims to understand how the immune system detects molecules produced by diverse microorganisms.

Funded Activity Details

Start Date: 01-01-2017

End Date: 19-10-2021

Funding Scheme: ARC Future Fellowships

Funding Amount: $680,648.00

Funder: Australian Research Council