ARC Future Fellowships - Grant ID: FT160100075

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/FT160100075

Funding Status
Active

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Funded Activity Summary

Bias and allostery at the calcium sensing receptor. This project aims to provide a mechanistic and dynamic picture of the structure, function and physiology of the human calcium sensing receptor (CaSR), which is critical for vertebrate life. By responding to chemicals in the body, it acts as a universal nutrient sensor to maintain extracellular calcium homeostasis and mediate biological functions, including neurotransmission, inflammation, digestion, blood pressure and development. However, it is not known how this single receptor controls the actions of multiple ligands to mediate numerous functions. By elucidating the roles of the CaSR and its ligands, this project aims to better understand fundamental physiological processes.

Funded Activity Details

Start Date: 01-01-2017

End Date: 30-01-2022

Funding Scheme: ARC Future Fellowships

Funding Amount: $680,640.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Animal Physiology - Systems | Pharmacology and Pharmaceutical Sciences | Basic Pharmacology

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences |

Other Keywords

Animal Physiology - Systems | Basic Pharmacology | Expanding Knowledge in the Biological Sciences | Pharmacology and Pharmaceutical Sciences

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