ARC Future Fellowships - Grant ID: FT150100342

Funding Activity

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Funded Activity Summary

The Protein Corona: Imaging the nanoparticle biological identity card. The project will determine how the intrinsic physico-chemical properties of nanoparticles translate into extrinsic biological properties through their interaction with physiological proteins in the body. This process is complex and poorly understood due to our inability to visualise it through standard imaging techniques. The project aims to develop a new tool to visualise, study, quantify and design the protein ‘corona’. These are the adsorbed protein layers that are rapidly formed in contact with biological liquids which allow cells to recognise and process nanoparticles. The proteins are dependent on factors such as size, shape, surface chemistry and biological history of the particles. Being able to ‘read’ and ‘write’ the protein corona would enable efficient cellular targeting of pharmaceutical drugs.

Funded Activity Details

Start Date: 01-04-2016

End Date: 03-04-2020

Funding Scheme: ARC Future Fellowships

Funding Amount: $674,352.00

Funder: Australian Research Council