ARC Future Fellowships - Grant ID: FT140100873

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/FT140100873

Funding Status
Closed

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Funded Activity Summary

Engineering Bioresponsive Hybrid Nanodevices using RNA, Peptides and Synthetic Polymers. This project aims to develop new microRNA polymer nanoassemblies with enhanced bioresponsive properties. Nanoengineered functional RNA-polymer materials can exploit both the recognition properties of RNA and the responsiveness of the polymer to tailor the structural and physicochemical properties of such systems. Further, targeting ligands (antibody, aptamers) tethered to the RNA-polymer nanoassembly could augment cellular uptake and delivery. The development of imaging and tracking methodology to accurately measure intracellular miRNA payload and localisation in a 3D tissue mimicking matrix is also planned.

Funded Activity Details

Start Date: 08-06-2015

End Date: 07-08-2019

Funding Scheme: ARC Future Fellowships

Funding Amount: $772,104.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Characterisation of Biological Macromolecules | Biomaterials | Biomedical Engineering | Nanochemistry and Supramolecular Chemistry

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Chemical Sciences | Expanding Knowledge in the Physical Sciences | Expanding Knowledge in the Biological Sciences |

Other Keywords

Biomaterials | Biomedical Engineering | Characterisation of Biological Macromolecules | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Chemical Sciences | Expanding Knowledge in the Physical Sciences | Nanochemistry and Supramolecular Chemistry

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