ARC Future Fellowships - Grant ID: FT140100730

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/FT140100730

Funding Status
Closed

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Funded Activity Summary

Plant peptides as modulators of invertebrate neurohormone receptors. Naturally-occurring peptides are widely distributed in many plants, but their biological role is often unclear. Circular plant peptides (called cyclotides) that share similarities with the neuropeptide oxytocin, and acts on its receptor, have been previously isolated. This signalling system is important for reproduction, development, and behaviour as well as water homeostasis. To elucidate the natural function of cyclotides. This project aims to characterise the pharmacological properties and biological effects of invertebrate receptors and their modulation by cyclotides. The notion that plants produce molecules to target invertebrate receptors is extremely appealing and will enhance knowledge about fundamental biological processes of plant-animal ecology.

Funded Activity Details

Start Date: 03-08-2015

End Date: 16-02-2018

Funding Scheme: ARC Future Fellowships

Funding Amount: $762,602.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Proteins and Peptides | Basic Pharmacology | Medicinal and Biomolecular Chemistry | Invertebrate Biology

ANZSRC Socio-Economic Objective (SEO)

Flora, Fauna and Biodiversity of environments not elsewhere classified | Expanding Knowledge in the Chemical Sciences | Expanding Knowledge in the Biological Sciences |

Other Keywords

Basic Pharmacology | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Chemical Sciences | Flora, Fauna and Biodiversity of environments not elsewhere classified | Invertebrate Biology | Medicinal and Biomolecular Chemistry | Proteins and Peptides

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