ARC Future Fellowships - Grant ID: FT140100398

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/FT140100398

Funding Status
Closed

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Funded Activity Summary

How microbes build their environments through evolutionary feedback. The fitness landscape, a key evolutionary concept, relates genes or traits to reproductive fitness. However, this has been challenged by organisms that distort the landscape by changing their environments. This project aims to develop a new mathematical model that restores the landscape concept by extending it to accommodate niche construction. This framework will be applied to microorganisms that alter their environments, for example, by provoking and subverting the host immune system, and by inducing behavioural change in hosts. These processes alter how natural selection operates on microbes and thus lead to important evolutionary feedback. The model will be used to examine antibiotic resistance, pathogen virulence and how microbiomes develop.

Funded Activity Details

Start Date: 01-01-2015

End Date: 18-10-2019

Funding Scheme: ARC Future Fellowships

Funding Amount: $808,160.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biological Mathematics | Applied Mathematics |

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Mathematical Sciences | Expanding Knowledge in the Medical and Health Sciences

Other Keywords

Applied Mathematics | Biological Mathematics | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Mathematical Sciences | Expanding Knowledge in the Medical and Health Sciences

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