ARC Future Fellowships - Grant ID: FT140100128

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/FT140100128

Funding Status
Closed

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Funded Activity Summary

Epigenetic regulation of centromere and telomere chromatin. Epigenetics is a system that turns genes on and off without sequence alterations in the DNA. This process works by attaching chemical tags, known as epigenetic marks, to DNA. Centromeres and telomeres are chromosomal DNA domains essential for faithful chromosome segregation and genome stability. Their function and structural integrity are tightly regulated by specific epigenetic marks. This project aims to assess the functions of key epigenetic factors including chromatin remodelers, histone variants and non-coding RNA in controlling centromere and telomere activity. The data should describe novel pathways that maintain the identity, transcription silencing, DNA replication fidelity and structural stability at these domains.

Funded Activity Details

Start Date: 01-01-2015

End Date: 31-12-2018

Funding Scheme: ARC Future Fellowships

Funding Amount: $694,104.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Epigenetics (incl. Genome Methylation and Epigenomics) | Genome Structure and Regulation | Genetics

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Medical and Health Sciences |

Other Keywords

Epigenetics (incl. Genome Methylation and Epigenomics) | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Medical and Health Sciences | Genetics | Genome Structure and Regulation

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