ARC Future Fellowships - Grant ID: FT130101797

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/FT130101797

Funding Status
Closed

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Funded Activity Summary

Extending X-ray Crystallography to Allow Structure Retrieval from Highly Disordered Crystals and Nanocrystals. X-ray crystallography is one of the most important tools in structural biology, responsible for over 80 per cent of the protein structures solved today. Obtaining X-ray diffraction data however is critically dependent on having large, high quality crystals. Many proteins, particularly membrane proteins, only form nanocrystals or crystals of poor quality which prevents their structure being solved. This project aims to combine ideas from X-ray coherent diffraction imaging and X-ray crystallography to develop a method that can be used for structure retrieval from nanocrystals or crystals which are highly disordered. A particular emphasis will be placed on solving the structure of membrane proteins which are of special importance in drug development.

Funded Activity Details

Start Date: 24-02-2014

End Date: 30-11-2018

Funding Scheme: ARC Future Fellowships

Funding Amount: $645,705.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Synchrotrons; Accelerators; Instruments and Techniques | Other Physical Sciences | Surfaces and Structural Properties of Condensed Matter | Biological Physics

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Physical Sciences | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Medical and Health Sciences |

Other Keywords

Biological Physics | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Medical and Health Sciences | Expanding Knowledge in the Physical Sciences | Other Physical Sciences | Surfaces and Structural Properties of Condensed Matter | Synchrotrons; Accelerators; Instruments and Techniques

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