ARC Future Fellowships - Grant ID: FT130101349

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/FT130101349

Funding Status
Closed

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Funded Activity Summary

Structural studies of host-pathogen interactions. The host-pathogen interface represents a major frontier for biomedical and biotechnological applications. This project aims to understand at the atomic level two such interfaces. In the first instance, the project will elucidate the molecular basis for inhibition of premature host cell death by poxviruses, in particular vaccinia and variola virus, the causative agent of smallpox. In the second instance, the aim is to understand how defensins, a major class of host defence molecules, recognise microbial targets such as fungi, and exert a potent antimicrobial effect. Understanding the precise molecular mechanisms operating at both these host-pathogen interfaces this will provide novel avenues for the design of antiviral and antimicrobial agents.

Funded Activity Details

Start Date: 01-01-2014

End Date: 31-12-2017

Funding Scheme: ARC Future Fellowships

Funding Amount: $749,918.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology | Structural Biology (incl. Macromolecular Modelling) |

ANZSRC Socio-Economic Objective (SEO)

Cotton | Infectious Diseases

Other Keywords

Biochemistry and Cell Biology | Cotton | Infectious Diseases | Structural Biology (incl. Macromolecular Modelling)

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