ARC Future Fellowships - Grant ID: FT130100540

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/FT130100540

Funding Status
Closed

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Funded Activity Summary

Examining novel cell signalling in the regulation of platelet structure and function. Pharmaceutical inhibition of platelet function is the primary therapy for prevention of arterial thrombosis – the most common cause of death and disability in Australia. However, current therapies have limited efficacy. Defining platelet activation mechanisms in order to rationalise more effective antithrombotic approaches is the major focus of this research. This project describes the first studies to examine the importance of a family of intracellular signalling enzymes, the Class II phosphoinositide 3-kinases, in platelet function. These studies will define the contribution of these enzymes to platelet production and function and will establish whether their inhibition is an attractive strategy for the prevention of arterial thrombosis.

Funded Activity Details

Start Date: 01-01-2014

End Date: 31-12-2017

Funding Scheme: ARC Future Fellowships

Funding Amount: $745,744.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cell Physiology | Haematology | Medical Physiology

ANZSRC Socio-Economic Objective (SEO)

Cardiovascular System and Diseases | Diabetes | Blood Disorders |

Other Keywords

Blood Disorders | Cardiovascular System and Diseases | Cell Physiology | Diabetes | Haematology | Medical Physiology

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