ARC Future Fellowships - Grant ID: FT130100204

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/FT130100204

Funding Status
Closed

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Funded Activity Summary

Site-specific Conjugation of Zirconium and Copper Complexes to Antibodies for Application in Diagnostic Imaging and Therapy. This project will focus on fundamental chemistry that underpins innovations in the synthesis of metal-based imaging and therapeutic agents. Radioactive isotopes of copper and zirconium can be used for either non-invasive diagnostic imaging or treatment of disease. However, it is essential that the diagnostic or therapeutic agent selectively localises in diseased tissue. This project aims to achieve the required selectivity by employing enzymatic site-specific bioconjugation reactions to build new imaging agents that feature ligands designed to safely bind radioactive isotopes fused to antibody derived targeting molecules.

Funded Activity Details

Start Date: 01-01-2014

End Date: 31-12-2017

Funding Scheme: ARC Future Fellowships

Funding Amount: $872,240.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Transition Metal Chemistry | Inorganic Chemistry | Bioinorganic Chemistry

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Chemical Sciences |

Other Keywords

Bioinorganic Chemistry | Expanding Knowledge in the Chemical Sciences | Inorganic Chemistry | Transition Metal Chemistry

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