ARC Future Fellowships - Grant ID: FT0991709

Funding Activity

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Funded Activity Summary

3D Structure determination of biomacromolecular assemblies from sparse data. This project has direct impact on pharmaceutical research: Biomacromolecular interactions are key points for pharmaceutical intervention and detailed structural knowledge of dynamic protein interactions can significantly accelerate drug development. Australia has invested in expensive instrumentation that can be used with new laboratory methods to obtain information on delicately balanced biomacromolecular interactions, and how they malfunction in disease. This project will provide a computational framework to increase the impact of this investment by integrating measurements from a range of novel technologies and developing understanding of changes in structure of large protein complexes in different functional states.

Funded Activity Details

Start Date: 31-03-2010

End Date: 30-03-2014

Funding Scheme: ARC Future Fellowships

Funding Amount: $788,800.00

Funder: Australian Research Council