Australian Laureate Fellowships - Grant ID: FL170100019

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/FL170100019

Funding Status
Closed

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Funded Activity Summary

Proteins in motion - new tools for biotechnology. This project aims to assess the function of proteins by monitoring their motions using new nuclear magnetic resonance (NMR) spectroscopy techniques. As snapshots of 3D protein structures have been determined by crystallography, the new tools are designed to analyse functionally important motions in solution. A facility for ultrafast (> 100 kHz) magic angle spinning NMR spectroscopy of proteins in the semi-solid state will bring cutting-edge know-how to Australia and allow the interrogation of 3D structure and dynamics in selected protein regions. The expected outcomes of the project will have immediate benefits for the rational engineering of biocatalysts and in the design of lead compounds in drug development.

Funded Activity Details

Start Date: 21-09-2017

End Date: 20-09-2022

Funding Scheme: Australian Laureate Fellowships

Funding Amount: $2,606,250.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Structural Chemistry and Spectroscopy | Biochemistry and Cell Biology | Structural Biology (incl. Macromolecular Modelling)

ANZSRC Socio-Economic Objective (SEO)

Human Pharmaceutical Treatments (e.g. Antibiotics) |

Other Keywords

Biochemistry and Cell Biology | Human Pharmaceutical Treatments (e.g. Antibiotics) | Structural Biology (incl. Macromolecular Modelling) | Structural Chemistry and Spectroscopy

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