Australian Laureate Fellowships - Grant ID: FL150100106

Funded Activity Summary

Bio-metrology and modelling of a complex system: the malaria parasite. Bio-metrology and modelling of a complex system: the malaria parasite: This fellowship project aims to develop a cross-disciplinary program to measure, model and manipulate a complex cellular system — sexual differentiation of the human malaria parasite. Combining life and physical sciences with powerful imaging techniques, the project seeks to develop quantitative biochemical, biophysical and modelling techniques to probe a complex system in a way previously not possible. It expects to integrate and correlate thousands of measurements of the dynamic processes inside cells and use these datasets to generate rigorous and sophisticated mathematical models that can predict drivers of commitment for transformation of the parasite to a sexual phase in preparation for transmission to mosquitoes. This holistic approach hopes to deliver new biotechnology and biomedical outcomes, including new ways to combat disease in livestock and humans.

Funded Activity Details

Start Date: 01-01-2016

End Date: 31-12-2021

Funding Scheme: Australian Laureate Fellowships

Funding Amount: $2,951,945.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Characterisation of Biological Macromolecules | Biochemistry and Cell Biology | Systems Biology | Cell Metabolism

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Mathematical Sciences | Infectious Diseases |

Other Keywords

Biochemistry and Cell Biology | Cell Metabolism | Characterisation of Biological Macromolecules | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Mathematical Sciences | Infectious Diseases | Systems Biology

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