Federation Fellowships - Grant ID: FF0883418

Funding Activity

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Funded Activity Summary

Membrane Attack Complex / Perforin like proteins in Defence, Attack and Developmental Biology. This proposal will result in a major advancement of knowledge, for example, in our understanding of the emerging links between immunity and development as well as the role and mechanism of function of the pore forming family of MACPF proteins in host defence, attack, embryo development and diseases such as cancer. These data will be crucial for developing approaches to control unwanted MACPF function, for example in disease such as diabetes or transplant rejection. Furthermore, a detailed understanding of how MACPF proteins assemble into rings and punch holes in membranes will facilitate the development of these proteins as technological tools.

Funded Activity Details

Start Date: 31-12-2008

End Date: 31-12-2013

Funding Scheme: Federation Fellowships

Funding Amount: $1,638,730.00

Funder: Australian Research Council