Discovery Projects - Grant ID: DP240103141

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP240103141

Funding Status
Active

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Funded Activity Summary

How lipid binding proteins shape the activity of nuclear hormone receptors. This project aims to explore how a family of lipid binding proteins control organ specific activation of nuclear receptors – receptors that play a key role in generating energy and are critical for life. The project will employ chemical, molecular, cell biology approaches to generate new knowledge about lipid binding protein-receptor interactions and how these complexes dictate receptor activation. The outcomes could provide a roadmap to design drugs that interact with the right protein in the right tissue and in doing so dramatically enhance drug specificity. This will benefit the success of drug treatments which require stimulation of a therapeutic response at a target site, and avoidance of potentially toxic activity at other locations.

Funded Activity Details

Start Date: 01-01-2024

End Date: 31-12-2026

Funding Scheme: Discovery Projects

Funding Amount: $720,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biologically active molecules | Pharmacology and pharmaceutical sciences | Basic pharmacology | Signal transduction

ANZSRC Socio-Economic Objective (SEO)

Other Keywords

Basic pharmacology | Biologically active molecules | Expanding Knowledge In the Biological Sciences | Expanding Knowledge In the Chemical Sciences | Pharmacology and pharmaceutical sciences | Signal transduction

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