Discovery Projects - Grant ID: DP240102812

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP240102812

Funding Status
Active

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Funded Activity Summary

Defining pathways that control T cell lifespan for long-term immunity. This project will investigate the cellular and molecular pathways regulating lifespan of tissue-resident memory T cells (Trm cells), a non-circulating T cell subset that play a crucial role in the frontline defence against infection. Significantly, how long Trm cells live is paramount to how long immunity is sustained. Using cutting-edge cellular and molecular techniques, the expected outcomes of this project include identification of the genes and processes that control lifespan. This should provide significant benefits in the basic knowledge of how longevity of immunity is regulated. This understanding will be useful for future immunotherapeutic applications, such as veterinary or human vaccines requiring maximal duration of immunity

Funded Activity Details

Start Date: 01-01-2024

End Date: 31-12-2026

Funding Scheme: Discovery Projects

Funding Amount: $817,768.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Veterinary immunology | Cellular immunology | Cell development proliferation and death | Immunology |

ANZSRC Socio-Economic Objective (SEO)

Other Keywords

Cell development proliferation and death | Cellular immunology | Expanding Knowledge In the Biological Sciences | Immunology | Veterinary Biological Preventatives | Veterinary immunology

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