Discovery Projects - Grant ID: DP240102506

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP240102506

Funding Status
Active

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Funded Activity Summary

From shape to function: how structured RNA defines insect flaviviruses. The goal of this project is to obtain an understanding of how insect-specific flaviviruses (ISFs) utilise viral noncoding RNAs to enable their replication in mosquitoes. These viruses only replicate in mosquitoes, and not in humans or animals. They can be employed as the biocontrol agents for mosquito-borne diseases as they make mosquitoes incapable of disease transmission. However, it is currently unknown how exactly insect-specific flaviviruses affect mosquitoes and this information is vital for informed design of ISF-based interventions. The project will generate new knowledge on functions of noncoding RNAs in ISFs that are hypothesised to have immunomodulatory role in mosquitoes. It will also train students and ECRs.

Funded Activity Details

Start Date: 01-01-2024

End Date: 31-12-2026

Funding Scheme: Discovery Projects

Funding Amount: $635,507.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Microbiology | Virology

ANZSRC Socio-Economic Objective (SEO)

Other Keywords

Control of Pests, Diseases and Exotic Species In Terrestrial Environments | Disease Distribution and Transmission (Incl. Surveillance and Response) | Microbiology | Virology

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