Discovery Projects - Grant ID: DP240102062

Funding Activity

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Funded Activity Summary

Deciphering the immune complexity that orchestrates T cell activation. The adaptive immune system consists of a complex cellular network that can efficiently distinguish exogenous required inputs, such as nutrients, from those that are potentially harmful like pathogens. Such ‘friend-foe’ discrimination has its molecular basis in a multitude of receptors with specificity to certain ligands. Critically, however, it is unclear how such discrimination is mechanistically regulated at the functional level. We have developed new and sophisticated experimental models that will allow us to systematically dissect and unfold the complexity of the adaptive immune system and address this critical knowledge gap. Expected outcomes will critically advance our general understanding of a fundamental biological principle.

Funded Activity Details

Start Date: 01-01-2024

End Date: 31-12-2026

Funding Scheme: Discovery Projects

Funding Amount: $525,194.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular immunology | Immunology |

ANZSRC Socio-Economic Objective (SEO)

Other Keywords

Cellular immunology | Expanding Knowledge In the Biological Sciences | Immunology