Discovery Projects - Grant ID: DP230102796

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP230102796

Funding Status
Active

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Funded Activity Summary

Defining the molecular basis for Salmonella persistence. Salmonella infections in animals and humans place significant burdens on the agri-food and healthcare sectors. All mammals and avian species can become chronically infected with Salmonella and such chronic carriage is a reservoir for disease and outbreaks in other animals and humans. Significant gaps in our understanding of Salmonella infection remain, including the molecular mechanisms involved in establishing a chronic carrier state. We identified several Salmonella specific genes and subsequent murine studies revealed that a Salmonella mutant lacking these genes is attenuated in mice and especially in the gallbladder. In this project we seek to understand the molecular basis for attenuation and the contribution of each protein to disease

Funded Activity Details

Start Date: 19-01-2023

End Date: 18-01-2026

Funding Scheme: Discovery Projects

Funding Amount: $589,519.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Microbiology not elsewhere classified | Animal production | Animal welfare | Veterinary bacteriology

ANZSRC Socio-Economic Objective (SEO)

Other Keywords

Animal production | Animal welfare | Expanding Knowledge In the Agricultural, Food and Veterinary Sciences | Microbiology not elsewhere classified | Prevention of Human Diseases and Conditions | Veterinary Biological Preventatives | Veterinary bacteriology

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