Discovery Projects - Grant ID: DP230102664

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP230102664

Funding Status
Active

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Funded Activity Summary

Beyond structure - solving conformational dynamics for intractable proteins. Proteins perform almost every task that enables the amazing complexity of cellular and whole organism physiology. These molecular machines perform this incredible array of tasks due to their ability to dynamically change shape. For the vast majority of these machines, we can only view a snapshot of the possible shapes they can adopt and can’t monitor how they change from one shape to another, which is critical for their functioning. This project aims to develop and apply a completely new method to visualise dynamic changes in protein shape which is not possible with current techniques. This will allow us to provide a new description and understanding of the function of proteins, which is fundamental to all biology.

Funded Activity Details

Start Date: 07-08-2023

End Date: 06-08-2026

Funding Scheme: Discovery Projects

Funding Amount: $483,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and cell biology | Structural biology (incl. macromolecular modelling) | Theoretical quantum chemistry | Receptors and membrane biology

ANZSRC Socio-Economic Objective (SEO)

Other Keywords

Biochemistry and cell biology | Expanding Knowledge In the Biological Sciences | Expanding Knowledge In the Chemical Sciences | Receptors and membrane biology | Structural biology (incl. macromolecular modelling) | Theoretical quantum chemistry

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