Discovery Projects - Grant ID: DP230102641

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP230102641

Funding Status
Active

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Funded Activity Summary

Synthesis and Characterisation of Tracer-Functionalised Nanoparticles . This project aims to engineer nanomaterials by utilising gold nanochemistry and neural tracing capabilities of plant-based, nontoxic proteins. In a significant departure from current nanomaterials being developed, functionalising nanoparticles with the tracers enable them to undergo path-specific axonal retrograde transport, transneuronal transport, and anatomical tract flow to bypass the blood-brain barrier. Microfluidics will be used to characterise the neuronal activities of the synthesised nanoconjugates of different sizes and compositions to understand their bio-interactions with axons, synapses, and neuromuscular junctions. The results will lead to a new class of functional nanomaterials as well as cell-based functional assays.

Funded Activity Details

Start Date: 01-04-2023

End Date: 31-03-2026

Funding Scheme: Discovery Projects

Funding Amount: $510,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Nanoscale characterisation | Materials engineering | Functional materials

ANZSRC Socio-Economic Objective (SEO)

Other Keywords

Expanding Knowledge In Engineering | Expanding Knowledge In the Chemical Sciences | Functional materials | Materials engineering | Nanoscale characterisation

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