Discovery Projects - Grant ID: DP230102422

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP230102422

Funding Status
Active

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Funded Activity Summary

How do cytokine receptors transmit signals? This project aims to determine the mechanisms of signal transmission by cytokine receptors using state-of-the-art microscopy techniques. Cytokines are small proteins that act as messengers between cells and play fundamental roles in biology. Cytokines bind to receptors on the surface of cells, producing a response within the cells. Yet, how the message is transmitted across the cell membrane is not well understood. Expected outcomes of this project include discovery of mechanisms general to cytokine signalling and new approaches to investigate cytokine biology. This new knowledge will benefit efforts to understand and modulate cytokine signalling in animals and humans, with future impacts in the agriculture, veterinary, and health sectors.

Funded Activity Details

Start Date: 01-01-2023

End Date: 31-12-2025

Funding Scheme: Discovery Projects

Funding Amount: $531,445.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and cell biology | Structural biology (incl. macromolecular modelling) | Signal transduction | Receptors and membrane biology

ANZSRC Socio-Economic Objective (SEO)

Other Keywords

Biochemistry and cell biology | Expanding Knowledge In the Biological Sciences | Receptors and membrane biology | Signal transduction | Structural biology (incl. macromolecular modelling)

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