Discovery Projects - Grant ID: DP230101979

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP230101979

Funding Status
Active

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Funded Activity Summary

Can we exploit mRNA modifications to control protein expression? Genes are encoded by DNA but are transcribed into a message called RNA before they can be translated into protein. RNA can be chemically modified at a gene-specific level, and this modification has been central to the success of RNA vaccines against COVID-19. Despite the importance of these modifications in cellular life and in biotechnology, the role of the most abundant RNA modifications is unclear. This project will investigate how we can exploit RNA modifications to modulate protein expression in a tractable single-celled organism with a small genome, Plasmodium. This information is important because understanding gene regulation is fundamental to all life, and the role of RNA modifications is emerging as integral to biotechnology.

Funded Activity Details

Start Date: 01-01-2023

End Date: 31-12-2025

Funding Scheme: Discovery Projects

Funding Amount: $397,996.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Host-parasite interactions | Gene expression (incl. microarray and other genome-wide approaches) | Genomics and transcriptomics | Genetics |

ANZSRC Socio-Economic Objective (SEO)

Other Keywords

Expanding Knowledge In the Biological Sciences | Gene expression (incl. microarray and other genome-wide approaches) | Genetics | Genomics and transcriptomics | Host-parasite interactions

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