Discovery Projects - Grant ID: DP230101113

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP230101113

Funding Status
Active

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Funded Activity Summary

Biophysics of the brain’s waste disposal system: Understanding why we sleep. This project aims to develop a new biophysical model of the brain, founded on the recently discovered glymphatic system responsible for waste disposal during sleep. It sets out to formulate, analyse, and validate rigorous new multiscale quantitative modelling – to advance the study of sleep and brain clearance dynamics, at timescales from hours to decades. Among expected outcomes are powerful models ready for application at both population and individual level, and testable predictions concerning the sleep patterns that lead to aggregation of waste in the brain and eventual cognitive decline. Project outcomes should also benefit society and the economy though translation into interventions for sleep disturbance – in future applied research.

Funded Activity Details

Start Date: 01-07-2023

End Date: 30-06-2026

Funding Scheme: Discovery Projects

Funding Amount: $385,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical and biological physics | Biological mathematics | Biological physics |

ANZSRC Socio-Economic Objective (SEO)

Other Keywords

Biological mathematics | Biological physics | Expanding Knowledge In the Biological Sciences | Expanding Knowledge In the Mathematical Sciences | Expanding Knowledge In the Physical Sciences | Medical and biological physics

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