Discovery Projects - Grant ID: DP230101056

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP230101056

Funding Status
Active

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Funded Activity Summary

Formation and clearance of endothelial cell-derived exophers. This project aims to investigate how cells that line the blood vessels release cellular wastes and their subsequent removal by immune cells. It is critical that cellular waste are removed in a timely manner as their accumulation inside the cell can interfere with normal cell functions. The intended outcome of the project is to generate fundamental new knowledge of the mechanisms by which cellular waste are efficiently removed. Expected outcomes encompass a paradigm-shift in understanding how cells that line the blood vessels dispose unwanted cellular contents. This should provide significant benefits including understanding how these specialised cells maintain the integrity of blood vessels and communicate with immune cells.

Funded Activity Details

Start Date: 01-01-2023

End Date: 31-12-2025

Funding Scheme: Discovery Projects

Funding Amount: $390,890.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and cell biology | Cell development proliferation and death | Biochemistry and cell biology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

Other Keywords

Biochemistry and cell biology | Biochemistry and cell biology not elsewhere classified | Cell development proliferation and death | Expanding Knowledge In the Biological Sciences

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