Discovery Projects - Grant ID: DP230101050

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP230101050

Funding Status
Active

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Funded Activity Summary

"Painting" the 3D proteome: folding, conformation and interactions. The project aims to develop a "residue painting approach", employing novel chemical biology reagents and advanced quantitative proteomics, to monitor changes in protein folding, conformations and interactions in cells, in response to stimuli. Proteins direct almost all functions required to sustain life. The project expects to map the dynamic 3D-structures of thousands of proteins that inform the networks they are in, and of the conformations they adopt. Expected outcomes include the development of novel biotechnology tools for protein structure and function analysis, the illumination of important cell biology pathways underpinning molecular responses to stimuli and stress, and the training of our next generation of scientists.

Funded Activity Details

Start Date: 01-01-2023

End Date: 31-12-2025

Funding Scheme: Discovery Projects

Funding Amount: $543,594.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Proteomics and intermolecular interactions (excl. medical proteomics) | Biochemistry and cell biology | Structural biology (incl. macromolecular modelling) |

ANZSRC Socio-Economic Objective (SEO)

Other Keywords

Biochemistry and cell biology | Expanding Knowledge In the Biological Sciences | Proteomics and intermolecular interactions (excl. medical proteomics) | Structural biology (incl. macromolecular modelling)

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