Discovery Projects - Grant ID: DP230100853

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP230100853

Funding Status
Active

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Funded Activity Summary

How do apicomplexan parasites steal amino acids from their hosts? The single-celled parasites that cause malaria and toxoplasmosis are adept at stealing nutrients from the host animals that they infect. How they do this is, however, poorly understood. This project seeks to identify the processes by which these parasites scavenge amino acids, an essential class of nutrient, from their hosts. Using innovative experimental approaches, the project aims to identify and characterise the parasite proteins that mediate the uptake of different amino acids into the parasite. The intended outcomes of the project are to provide comprehensive insights into a fundamental aspect of parasite biology, and inform strategies to treat the diseases caused by these parasites by cutting off their nutrient supply.

Funded Activity Details

Start Date: 01-01-2023

End Date: 31-12-2025

Funding Scheme: Discovery Projects

Funding Amount: $862,272.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Infectious agents | Biochemistry and cell biology | Cell metabolism | Receptors and membrane biology

ANZSRC Socio-Economic Objective (SEO)

Other Keywords

Biochemistry and cell biology | Cell metabolism | Expanding Knowledge In the Biological Sciences | Infectious agents | Receptors and membrane biology

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