Discovery Projects - Grant ID: DP230100675

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP230100675

Funding Status
Active

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Funded Activity Summary

Cell–fluid interaction: inside and outside cells. The project aims to measure mechanics at the cellular level using a combination of optical tweezers for measurement of nano-scale environment around/inside cells and light-sheet microscopy for imaging. The project expects to generate new knowledge about movement of cells through their environment, relating to collective behaviour which is of importance in understanding infections and formation of biofilms. Expected outcomes include deepened understanding of an enigmatic process conserved from amoebae to humans, by which cells ‘drink and eat’ by ‘gulping’ fluid and supplement their nutrient intake by degrading proteins and cell debris. It will generate new knowledge of these processes to better understand how mechanics affects cellular life.

Funded Activity Details

Start Date: 08-08-2023

End Date: 07-08-2026

Funding Scheme: Discovery Projects

Funding Amount: $565,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Classical physics | Biological physics | Nanobiotechnology | Classical and physical optics

ANZSRC Socio-Economic Objective (SEO)

Other Keywords

Biological physics | Classical and physical optics | Classical physics | Expanding Knowledge In the Biological Sciences | Expanding Knowledge In the Physical Sciences | Nanobiotechnology | Scientific Instruments

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