Discovery Projects - Grant ID: DP220103632

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP220103632

Funding Status
Active

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Funded Activity Summary

Combating Antimicrobial Resistance with Bismuth, Gallium and Indium. This research project focuses on the design, development, and application of new bismuth, gallium and indium compounds as antimicrobial agents. These metals act as iron mimics in vivo and can exert antimicrobial activity while displaying low systemic toxicity in humans. The project aims to exploit this, and the inability of microbes to easily develop resistance towards metals, to combat bacteria for which modern drugs are rapidly becoming ineffective, as highlighted in the WHO and US Centre for Disease Control list of critical and priority pathogens. The intended outcome is that efficacy will be driven through advances in synthetic and structural chemistry, discovering the mode of action, and creating anti-infective coatings and hydrogels.

Funded Activity Details

Start Date: 01-07-2022

End Date: 30-06-2025

Funding Scheme: Discovery Projects

Funding Amount: $635,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Organometallic Chemistry | Functional Materials | Main Group Metal Chemistry | Inorganic Chemistry |

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Chemical Sciences | Expanding Knowledge in the Medical and Health Sciences

Other Keywords

Expanding Knowledge in the Chemical Sciences | Expanding Knowledge in the Medical and Health Sciences | Functional Materials | Inorganic Chemistry | Main Group Metal Chemistry | Organometallic Chemistry

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